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At elevated temperatures, even a few degrees above refrigeration, the rate of hydrolysis measurably increases per Arrhenius kinetics

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Reactive oxygen species (ROS), peroxide anions, and hydrogen peroxide are normal products of the mitochondrial respiratory chain, which mainly produced catalase (CAT) complex I and III, and, as a highly active and diffuse species, ROS is involved in various signal transduction cascades and adaptive stress responses [24]

References Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA